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The schematic representations refer to the inhibitors that belong to: a-d) Kunitz family (BPTI-type), e-i) Kazal family (PSTI-type), j) inhibitor from Streptomyces, k) Kunitz-type family from soybean, l) Bowman-Birk family, m) potato type I family, n) potato type II family Cysteine residues in homologous proteins (those of common ancestry) are very conservative according to PAM 250 scoring matrix (Fig 4)

Current guidelines stress the significance of these tests in older adults, who may present with atypical symptoms or multiple comorbidities that complicate diagnosis

A competition study was initiated with several derivatives of the D-Nle-X-Ile-NH(CH 2 ) 5 CONH 2 family